336 Tumour associated macrophage recruitment in SCC

Adipokines Involved in Macrophage Recruitment

Tumour-associated macrophage polarisation and re-education with immunotherapy.

Monocytes/macrophages constitute important contributors of cancer-associated inflammation. Through their plasticity and capacity to become polarised by tumours towards less activatory and more immunosuppressive (M2) phenotypes, tumour-associated macrophages (TAM) are thought to support tumour progression. Orchestrated by T helper 2 (Th2)-biased stimuli, macrophage recruitment, activation and po...

Monocyte recruitment and macrophage proliferation in atherosclerosis.

Copyright © Polskie Towarzystwo Kardiologiczne INTRODUCTION In the famous ‘Atlas of atherosclerosis: progression and regression’, Herbert Stary [1] outlines in remarkable detail the development of human atherosclerosis. The photographs depicting lesions at all stages of development, from newborns to the elderly, capture in stunning detail the complexity of an evolving disease. Type I lesions de...

P112: Tumour Associated Macrophages and Vasculogenic Mimicry: A New Insight in Glioblastoma Treatment

Glioblastoma is one of the most common brain tumors in adults with poor prognosis, aggressiveness, and treatment resistance. Vasculogenic mimicry (VM) consists of generating vascular-like channels by tumor cells, independent of endothelial angiogenesis. Studies showed in glioblastoma, the proportion of VM to all vascular channels is associated with poor prognosis and higher invasiveness levels....

Tumour-associated and non-tumour-associated microbiota in colorectal cancer

OBJECTIVE A signature that unifies the colorectal cancer (CRC) microbiota across multiple studies has not been identified. In addition to methodological variance, heterogeneity may be caused by both microbial and host response differences, which was addressed in this study. DESIGN We prospectively studied the colonic microbiota and the expression of specific host response genes using faecal a...